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Ligustilide A

CAS No. 81944-09-4

Ligustilide A ( cis-Ligustilide )

Catalog No. M24810 CAS No. 81944-09-4

Ligustilide A, an active ingredient isolated from the medicinal plants Angelica acutiloba and Cnidium officinale, inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ligustilide A
  • Note
    Research use only, not for human use.
  • Brief Description
    Ligustilide A, an active ingredient isolated from the medicinal plants Angelica acutiloba and Cnidium officinale, inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.
  • Description
    Ligustilide A, an active ingredient isolated from the medicinal plants Angelica acutiloba and Cnidium officinale, inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.
  • Synonyms
    cis-Ligustilide
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    81944-09-4
  • Formula Weight
    190.2
  • Molecular Formula
    C12H14O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (525.65 mM; Need ultrasonic)
  • SMILES
    CCC/C=C\1/C2=C(C=CCC2)C(=O)O1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wu Z, Uchi H, Morino-Koga S, Nakamura-Satomura A, Kita K, Shi W, Furue M. Z-Ligustilide inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation. Exp Dermatol. 2014 Apr;23(4):260-5. doi: 10.1111/exd.12360. PubMed PMID: 24588654.
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